Framework: Y Combinator Startups to Build
- A Way to End Cancer
- AI for Personal Finance
- AI for Scientific Advancement
- AI Native Enterprise Software
- AI Personal Assistant
- AI Personal Tutor for Everyone
- AI Research Labs
- AI Residential Security
- AI to Build Enterprise Software
- AI Voice Assistants for Email
- AI-Aided Engineering Tools
- Applying Machine Learning to Robotics
- Commercial Open Source Companies
- Developer Tools Inspired by Existing Internal Tools
- Eliminating Middlemen in Healthcare
- Explainable AI
- Fintech 2.0
- Foundation Models for Biological Systems
- Full-stack AI Companies
- Government Software
- Healthcare AI
- Infrastructure for Multi-Agent Systems
- Internal Agent Builder
- LLMs for Chip Design
- LLMs for Manual Back Office Processes in Legacy Enterprises
- Manufacture in the USA
- More Design Founders
- New Defense Technology
- New Enterprise Resource Planning Software
- New Space Companies
- One Million Jobs 2.0
- Public Safety Technology
- Retraining Workers for the AI Economy
- Small Fine-tuned Models as an Alternative to Giant Generic Ones
- Software Tools To Make Robots
- Spatial Computing
- Stablecoin Finance
- Stablecoins 2.0
- The First 10-person, $100B Company
- The Future of Education
- The Managed Service Organization Model for Healthcare
- Using LLMs Instead of Government Consulting
- Using Machine Learning to Simulate the Physical World
- Video Generation as a Primitive
- Voice AI
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